After 50, most men begin to notice changes in urination: their urine stream becomes weaker, they feel the urge to urinate more often, they have to get up one or more times during the night to urinate... these are clear signs that their prostate needs special care, such as Opti +50 Prostaplus. How to use: Take 1 tablet daily, without chewing, accompanied by 1 or 2 large glasses of water.